History · Chapters 1–4
Before Ecstasy; From Private Rooms to Public Dance Floors; A Name on a Tablet; A Substance Between Categories — from a 1912 chemical intermediate to what a market sample can establish.
Published · Ebook edition available · The Spore Patch Ltd
The Psychedelic Evidence Atlas
Volume VI · MDMA
The sixth volume of Richard L. Pope's nine-volume audit follows MDMA through history, chemistry, subjective effects, harms and therapeutic investigation — a molecule that has travelled through laboratories, dance floors and consulting rooms.
Its organising question is how a claim earns its place: what was administered, who was studied, what changed, compared with what, and over which interval.
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The governing principle
Evidence belongs first to the thing actually studied
MDMA-assisted therapy is not the same intervention as MDMA alone, and a defined research preparation is not the same as a substance encountered outside that setting. Those distinctions run throughout the volume, and each chapter keeps the conditions of the observation in view.
Volume VI structure
How the MDMA volume is built
An introduction, twenty-four chapters and chapter source notes — moving from history and bodily effects to social experience, harms and clinical research, then to follow-up, blinding, professional responsibility, regulation and other therapeutic uses.
The molecule and the body · Chapters 5–6
What the Molecule Does and The Body Clock — transporters rather than receptors, and following a swallowed molecule through the body.
Social and emotional experience · Chapters 7–9
Feeling Close; Music Touch and the Social World; Fear Memory and Emotional Openness — what empathy measures, and the results that complicate the story.
Harms · Chapters 10–14
The Following Days; The Body Overwhelmed; Other Drugs Other Conditions; Neurotoxicity; Repeated Use — each harm given its own measurement.
Clinical research · Chapters 15–19
Why PTSD; What the Treatment Contains; Early Clinical Evidence; Phase III; What Lasts — from the first pilots to the pivotal trials and their follow-up.
Responsibility and regulation · Chapters 20–24
Unblinding; Trust Power and Protection; The Regulatory Test; Beyond PTSD; What the Evidence Can Carry.
Apparatus
Numbered citations and chapter source notes
Numbered citations lead to source notes collected at the back of the book, with numbering starting again in each chapter. The notes identify study designs, limitations and selected source checks.
Selective, not systematic
The volume is a selective, evidence-led investigation, not a systematic review. Selected checks were undertaken through 2 November 2026; that date does not imply exhaustive coverage of all research or regulatory developments up to that day.
Citation is not endorsement
Citation does not imply that every table or supplement was checked. Dated regulatory decisions are discussed in their historical context, and later developments may change the interpretation of material in this edition.
The author
Richard L. Pope
Author of The Fungal Evidence Atlas and The Psychedelic Evidence Atlas, published by The Spore Patch Ltd. No academic affiliations, qualifications, awards or endorsements are claimed, and none should be inferred.
The Psychedelic Evidence Atlas, Volume VI: MDMA. First edition, November 2026. Published by The Spore Patch Ltd as a reflowable EPUB 3 ebook. Copyright © 2026 Richard L. Pope.
Availability
Published · Ebook edition available
This edition is a digital publication only. The Spore Patch Ltd sells digital publications and does not sell mushrooms, supplements or remedies.
- Title
- The Psychedelic Evidence Atlas — Volume VI: MDMA
- Publisher
- The Spore Patch Ltd
- Edition
- First edition, November 2026
- Format
- Reflowable EPUB 3 ebook
- Price
- £7.99
- File size
- Approximately 0.6 MB
- Contents
- Introduction, twenty-four chapters and chapter source notes
- ISBN
- No ISBN assigned for this edition
- Delivery
- Download link delivered by email after checkout
This book provides information and critical discussion. It does not provide individual medical advice or instructions for using MDMA. Decisions about treatment or prescribed medicines should be discussed with an appropriately qualified clinician.